Archive for the ‘Pain’ Category

NSAIDs For Canine Osteoarthritis Prove Effective But Not Without Major Risks

Jack Russel asked:




Non-steroidal anti-inflammatory drugs (NSAIDs) are the standard form of treatment for dogs suffering from osteoarthritis. For years, NSAIDs have been prescribed to dogs with this ailment because of their effectiveness in dealing with joint pain.

Over the years, however, more and more studies are emerging that NSAIDs may not be the best treatment for canine osteoarthritis after all. NSAIDs do work by blocking the formation of chemicals in a dogs body which cause inflammation of the joints and joint pain in the affected area. Just like in any disease, the best form of treatment for osteoarthritis should be something that works to repair the source of the disease itself, in this case, degenerating cartilage in the joints. NSAIDs cannot do that. All it can do is to try to stop the inflammation and control the pain. Common names of pain killers used in treatment are Rymadol, Tramadol, and Deramaxx. But take a look at these side effects direct from the Deramaxx web site:

Vomiting, anorexia, diarrhea, melena, inappetence, hematemesis, hematochezia, weight loss, nausea, gastrointestinal ulceration, gastrointestinal perforation, salivation. Hematological: Anemia, thrombocytopenia. Hepatic: Hepatic enzyme elevations, decreased or increased total protein and globulin, decreased albumin, decreased BUN, hyperbilirubinemia, icterus, ascites, pancreatitis. Neurological: Lethargy, weakness, seizure, ataxia, tremor, nystagmus, mydriasis. Sensory: Vestibular signs, glazed eyes, uveitis. Behavioral: Aggression, apprehension. Urinary: Azotemia, polydipsia, polyuria, hematuria, low specific gravity, urinary incontinence, urinary tract infection, renal failure. Cardiovascular: Bradycardia. Respiratory: Tachypnea, coughing. Dermatological/Immunological: Fever, edema, facial/muzzle edema, pruritis, urticaria, moist dermatitis, erythema, dermal ulceration/necrosis.

Half of these symptoms, I have no idea what they are, but I am certain they are of a detrimental nature to the happiness of your pet. Moreover, studies are also stating that NSAIDs may pose even more serious side effects that can lead to permanent damage in dogs. Such damages include ulcers, gastrointestinal bleeding, liver damage and kidney damage which can lead to death. While we will do anything to help our pets feel happy and pain free, this path of powerful drugs for treatment may be more than we bargained for.

Because of these side effects, more dog owners and more veterinarians are looking for alternatives to NSAIDs to help in dealing with canine osteoarthritis. The one that stands out as most effective and with few, if any, side effects, are natural supplements with glucosamine and chondroitin. Studies have concluded that the combination of these two supplements effectively control joint pain better than NSAIDs. Glucosamine treats osteoarthritis right at its source, the degenerated cartilage tissue in the dogs joints. Glucosamine is a building block of cartilage tissue and also acts as a catalyst to the formation of new cartilage tissue. In effect, glucosamine helps treat osteoarthritis by assisting in the repair of damaged and degenerated cartilage tissue.

As for chondroitin, chondroitin works by keeping harmful enzymes that cause inflammation away from the joints. It also aids in the tasks to be done by glucosamine by attracting liquids that will provide lubrication to the joints.

Glucosamine and chondroitin, as clearly stated above, treat osteoarthritis by dealing with the source of the ailment. Pain relief comes from healing, not masking pain.

Do glucosamine and chondroitin display side effects on the same degree as those of NSAIDs? The answer is that none are discovered yet, and most likely, there will be few and not nearly as severe as the side effects of NSAIDs. Glucosamine and chondroitin are natural compounds both found naturally in the dogs body.

Butalbital Blog

Pain Medication You Can Legally Order Online

David Altfeder asked:




Millions of American live with pain. Chronic pain, daily pain, short term severe pain. Of all the medications sold by online pharmacies, by far the most common type is pain relievers. You might think then that online pharmacies are a great source of pain relievers.

Well, did you know the Drug Enforcement Agency of the United States (DEA) has busted and close over 5000 online pharmacies? Did you know that many online pharmacies sell counterfeit medication? Did you know it is a federal crime for you to order prescription drugs from outside the United States?

It is true, online pharmacies are a great source of pain relief medication. This article teaches you to order pain medication legally, from within the United States, with a legal prescription. It’s the only way to go!

First, the caveats: You cannot legally order medication from outside the United States, even if you have a prescription. We always hear about the elderly taking buses to Canada to buy cheap medicine. The fact is, as of this writing, this course is illegal. Also, you cannot legally order medicine from a pharmacy without a prescription. Many online pharmacies (including my own) have physicians on staff who review your medication request and write you a prescription if they think it’s safe. In addition, NEVER order narcotics through the mail. Forget codeine, Tylenol #3, oxycontin, demerol, percodan and percocet. You can be charged with a federal crime for buying these substances. Lastly, regardless of the medication you buy, be sure to read the package insert (or a monograph on my web site). Drugs interact with each other and with your body- the package insert will tip you off to potentially dangerous behavior with respect to the medication you ordered.

The following are quick summaries of common pain relief drugs you can order through the Internet with very little risk:

Fioricet (butalbital)

Fioricet is a combination drug. It is made up of acetaminophen, caffeine and butalbital. Acetaminophen is the same medication in Tylenol You know caffeine from coffee (or even your favorite candy bar.) Butalbital is a mild barbiturate. It relaxes you.

Medical Science does not have an explanation for the reason this combination of drugs works so well, but the fact is Fioricet (and its generic form butalbital) is highly effective for tension headache. Presumably, it relaxes the muscles in the head and neck which typically tighten during tension headaches.. This is the top selling drug at our pharmacy month after month- it really helps headaches!

Soma (carisoprodol)

Soma is a muscle relaxant. It acts by blocking electrical signals among nerves in the reticular formation of the brain and in the spinal cord. Carisoprodol, combined with rest and physical therapy, is prescribed for the short term relief of painful muscle conditions- particularly muscle spasm (where the muscle tightens and does not relax). Most back strains result in muscle spasm, so patients find carisoprodol highly effective in relieving back pain.

Celebrex (celecoxib)

Celebrex is used in the treatment of symptoms of arthritis. This includes joint pain, stiffness, swelling and inflammation. The medication does not cure arthritis, but does provide symptomatic relief. It s a nonsteroidal anti-inflammatory drug (NSAID) which relieves pain and inflammation. The drug works by blocking the production of prostaglandins in the body. Prostaglandins contribute to the pain and swelling associated with arthritis.

Ultram (tramadol)

Ultram is used for treatment of moderate to severe chronic pain. It binds to the opiod receptors on nerves (the same mechanism used by narcotics), but it has a far lower potential for dependency. It’s the closest medication to a narcotic you can order legally in the US online. It is not a NSAID (nonsteroidal anti- inflammatory drug) and does not carry the risk of stomach ulceration and internal bleeding which can accompany the use of such medications. It is often prescribed for pain associated with shingles, fibromyalgia and other chronic diseases.

Ulracet

Ultracet is a combination of acetaminophen and tramadol. It is typically prescribed for the short term (up to five days) relief of moderately severe acute pain. It is often prescribed for post-surgical pain or after dental procedures.

The ultram mechanism as described above is very similar to the mechanism employed by narcotics. Acetaminophen of course is the active ingredient in Tylenol. It works by increasing the threshold to pain (i.e. it takes more pain stimulus to cause the sensation of pain). These two drugs work by different mechanisms, and they combine to be more effective than either drug alone.

Pain relief medication can be ordered safely online, but one should exercise appropriate caution before doing so. Specifically, it’s important to determine whether you need to see a physician before ordering pain medication. If you have a sudden onset of pain which is not readily explained, you should consult a physician first. If in doubt, go to the emergency room. If however you are a patient who has been diagnosed, and pain is a recurring problem, you can conveniently order pain medication online- typically at a lower cost than the combined cost of a doctor’s appointment and the medication itself.

Copyright 2005 DeepDiscountPharmacy.net

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Tooth Pain

Marcus Peterson asked:




Tooth pain or toothache usually refers to the pain occurring around the teeth or jaws. In most instances, toothaches are caused by either tooth or jaw problems, such as a cavity, a cracked tooth, an exposed tooth root, gum disease, disease of the jaw joint, or spasms of the muscles used for chewing. The severity of a toothache can range from mild to chronic and excruciating. The pain may be aggravated by chewing or by extreme cold or heat. A thorough oral examination, including dental x-rays, can help determine the cause, whether the toothache is coming from a tooth or a jaw problem.

Sometimes, pain around the teeth and jaws can be symptoms of diseases of the heart, such as angina or heart attack, or of the ears, such as inner or external ear infections, and sinuses, like air passages of the cheek bones. The pain of angina, which is due to the inadequate supply of oxygenated blood to the heart muscle because of narrowing of the arteries, usually occurs in the chest or arm. However, in some cases of angina, a toothache or jaw pain, are the only symptoms of heart problem.

Infections and diseases of the ears and sinuses can also cause toothache. Thus, evaluations by both dentists and doctors are sometimes necessary to diagnose medical illnesses causing toothache. Otherwise the common dental causes of toothache include dental cavities, dental abscess, and gum diseases, irritation of the tooth root, cracked tooth syndrome, temporo-mandibular disease, impaction, and eruption.

The most common cause of toothaches is however, dental cavities. Dental cavities are holes in the two outer layers of a tooth, called the enamel and the dentin. The enamel is the outermost white hard surface and the dentin is the yellow layer lying just beneath the enamel. Both layers serve to protect the inner living tooth tissue called the pulp, where the blood vessels and nerves reside. Certain bacteria in the mouth convert simple sugars into acidic solutions. The acid softens, and, along with saliva, dissolves the enamel and dentin, creating small holes, or cavities. Small, shallow cavities are not that painful and may go unnoticed by the patient. The larger deeper cavities tend to collect food particles. The inner living pulp of the affected tooth thus gets irritated by bacterial toxins or by foods that are cold, hot, sour, or sweet, causing toothache. Toothaches from these larger cavities are the most common reasons for visits to dentists.

Treatment of a small and shallow cavity usually involves a dental filling, using amalgam, composite resin or glass ionomer cement. However, in the case of a larger cavity, an onlay or a crown is capped on the affected area. Treatment of a cavity that has penetrated deep enough and injured the pulp requires either a root canal procedure or extraction of the affected tooth. Injury to the pulp can lead to death of pulp tissue, resulting in tooth infection, or dental abscess. The root canal procedure involves removing the dying pulp tissue, thus avoiding or removing possible tooth infection, and replacing it with an inert material. This procedure is used in an attempt to save the dying tooth from extraction and is very painful.

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What the Heck is Fibermyalgia?

Nathan Wei asked:




The cause of fibromyalgia (FM) is unknown but theories pointing toward abnormal hypothalamic pituitary axis function or dysfunction of neurotransmitter pathways in the brain are currently popular.

Several studies have demonstrated different abnormalities in central nervous system functioning. Abnormal sleep studies showing alpha intrusion during delta (stage 4) sleep and a reduction of rapid eye movement (REM) sleep have been seen. In addition, abnormal SPECT scans have suggested lower blood flow to the thalamus and caudate nucleus in the brains of fibromyalgia patients.

Approximately 2 percent of the population has fibromyalgia. About 80 percent of patients with fibromyalgia are women. While fibromyalgia may occur as a primary condition, it is also a secondary condition, occurring in as many as 30 percent of patients with systemic lupus erythematosus and rheumatoid arthritis.

Patients with fibromyalgia complain of generalized pain affecting both sides of the body and both the upper as well as lower part of the body.

Pain tends to be aggravated by weather changes as well as by stress.

While patients will complain of subjective joint swelling, objective swelling is absent.

Sleep disturbance occurs in almost all patients. Complaints of chronic fatigue and non restorative sleep (feeling as if they haven’t slept) are common. Sleep apnea may aggravate the situation.

Tender trigger points are noted in all patients. A patient with 11 of 18 tender trigger points fulfills a major diagnostic criterion for the diagnosis of fibromyalgia. These trigger point tender areas are stereotypic meaning the same areas are tender in all patients with the diagnosis of FM..

Other symptoms include migraine headache, decrease in short term memory, cognitive dysfunction, blurred or double vision, hypersensitivity to sound and smells, shortness of breath, chest pains, palpitations, irritable bowel, irritable bladder, painful menses, painful urination, multiple drug allergies, multiple sensitivities to chemicals.

Laboratory testing will not be diagnostic. However, laboratory testing will help to exclude other conditions such as polymyalgia rheumatica, hypothyroidism, rheumatoid arthritis, systemic lupus erythematosus, etc., that might masquerade as fibromyalgia. FM is a diagnosis of exclusion so it is imperative that other possible causes of aches and pains are ruled out.

Imaging tests may also be helpful in establishing the presence or absence of FM.

Treatment must be individualized. Most patients will respond to a combination of non impact aerobic exercise (swimming, stationary bike, elliptical trainer), cognitive behavioral therapy, and medication.

Medications that have been found to be helpful include tricyclic antidepressants in low doses, muscle relaxants such as cyclobenzaprine, also in low doses, and selective serotonin reuptake inhibitors (SSRIs).

Other medicines such as gabapentin and tramadol may also be helpful.

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Accessible Pain Medication Online

Josh L Mckinley asked:




Pain is a challenging condition most American patients have to deal with. People can suffer any condition from everyday pain to long term pain. If you find yourself in an unbearable ache, you can be tempted to go online and buy from an online drug store. Nonetheless, huge risks occur with purchasing painkillers from the net. The pain killer you take online could be fake in its type. In fact, over 5000 online pharmaceuticals have been caught by the Drug Enforcement Agency of the USA. Aside from the fake ingredients of the medicines, many people self prescribe their own pain killers. They don’t bother seeing a physician to get an apt prescription for their situation. You can also be legally accused for buying oxycontin, Percocet, Demerol, and Tylenol. In order to avoid these risks, there are specific precautions you may implement when buying from the net.

In spite of these dangers, there are certain pain medications you can still purchase from online pharmaceuticals. You won’t experience any trouble having these mailed to your house.

One possible and harmless to order painkiller is Fioricet. This is a mixed medicine made of caffeine, butalbital, and acetaminophen. This medication functions best against tension headaches. The different ingredients act by relieving your head and neck, the parts usually tight during tension headaches. People who experience incredible migraines should opt for this medicine.

You can also opt to take Celebrex. Celebrex is able to remedy stiffness, inflammation, swelling, and pain from arthritis symptoms. These signs are relieved with a nonsteroidal anti-inflamattory drug (NSAID), inhibiting the body’s prostaglandins production. The prostaglandin is responsible for causing the pain and swelling symptoms.

Soma or carisoprodol is a muscle relaxant recommended for short run muscle trouble conditions. Its relaxing functions will stop the contraction from the muscle spasm. Electrical signals found in the brain’s reticular formation and the spinal cord are blocked. Those with back pains are usually recommended carisoprodol. This pill is best combined with physical therapy.

Constant pains are treated with ultram or tramadol. Ultram sticks to the opiod receptors, similar to how narcotics work. It is most likely the most authorized type of a narcotic that can be ordered online in the US. It doesn’t have the danger of enabling internal bleeding and ulceration, which are commonly associated with this medicine’s class. Expect to take this if you have fibromyalgia, shingles, or other chronic conditions.

When ordering for any of these medicines, search for the sites that include insurance billing and price checking. They should also have automatic refill systems, prescription confirmation (from your doctor), and pharmacist advices. You should also ensure that you visit a doctor to have a proper pain medication prescription. Only order from websites that need a prescribed note before they actually mail you your order. Always study the online pharmacy site before implementing your order. Your instinct will usually inform you if the site is a scam or not. Do not undergo the risk of buying dangerous or useless pain killers from a supposed to be affordable online pharmacy.

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